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MacX YouTube Downloader. Microsoft Office YTD Video Downloader. Adobe Photoshop CC. VirtualDJ Avast Free Security. WhatsApp Messenger. Talking Tom Cat. Clash of Clans. Subway Surfers. Files by Google allows you to manage, find, share, and back your files in the cloud to free up space.

Files by Google is the all-in-one management app for your files. Quickly find your files by using filters instead of folders like other file managers. Arrange your files by size to quickly get the largest one and browse through your GIFs easily.

You can share files with anyone close by that has the app without using the internet. Simply pair both devices and start sending them. Art Files is perfect for production artists or anyone who works with graphics files and needs the portability of sending documents to others for editing or printing.

Its simple, straight-forward user-interface is sure to make file collection nightmares a thing of the past. Art Files has the unique ability to collect several documents at once, saving precious time when only minutes stand between overnighting your artwork to the printer and having to hire a high-price door-to-door courier to meet your deadline.

In addition to saving time, this feature also cuts down on disk space by collecting shared images and fonts between documents only once. And you can even extend its preview capabilities using Quick Look plug-ins like Art View. Well, you can be sure of it. Download now the software that will simplify your life: searching and applying the covers for you with a mouse click.

Not limited to album cover, taghycardia is a free MP3 auto tagging utility that fixes the tags in downloaded music with a few clicks. Last but not least, Taghycardia is also able to get lyrics from online sources automatically to embed into the tags for reading song texts on your mobile device while it plays the music. The app seeks out missing album covers and saves them on a disk or in an audio file. If multiple options are found, the tool asks you to choose the best solution from the album art found.

As you might already know — The Crab is a small utility that can help you organize your music albums using various music data sources, such as Amazon or Discogs. Then, hit convert after you have adjusted the formatting. Download your JPG with just a click of a button. What Program Opens Art Files?

A compressed archive is available for download. Johnson-Grace compressed files are available on AOL. In the beginning, Raster Graphics were used as publishers. A view of the torso. I made a scrapbook for Central Point. The publisher of this artwork is pfs. Your files end in. Using double-click, launch. Filename extension.

ART File? You can access Songs within the Music app on your Mac by clicking the Songs icon on the left sidebar.
























In addition to all that, you get to explore the wild environments and impressive graphics of this action-packed adventure game. Keep in mind that you will need a high-end PC to handle the versatile Unreal Engine 4 that powers the visuals and other elements of the game.

If you have a modern gaming PC, then the better your experience playing the game. Minecraft : Minecraft is a sandbox video game that features both survival and creative modes. You have the liberty to build your own wall and shelter of protection as you like. In addition to the adventure theme, it features educational content that you can learn from as you play. Absolute Survival: In Absolute survival, you only get to succeed by shooting anything that moves.

Take no prisoners. Kill everybody that stands in your way. The game is pretty tough with the many horrible, blood-thirsty monsters and creatures out to get you. The game is set in a harsh, unforgiving post-apocalyptic world overrun by the undead. Your aim is to fight your way through and survive total annihilation by the zombie horde. Avoid downloading cracked versions of the app, as these may sometimes contain spyware, malware, or viruses. Use the download instructions above to get the game free of viruses.

Adventure Games Free Download Latest. You can also download Open World Games Here. In Ark Survival Evolved free download with multiplayer the developers have greatly focused on the visual appearance of animals and other creatures.

At the initial stages of Ark Survival Evolved free download, players will have to build a basic base so as to rest and stay safe from other creatures while resting. However, in the advanced stages of the game, players can also attack other villages to capture them and expand their kingdom territory.

You can also download other Adventure Games Here. Save my name, email, and website in this browser for the next time I comment. News Games Android Cheats Guide. Update 1 Extract 2 Run setup. PC Download [ Direct download link Windows ]. You Might Also Like:. Download Car Mechanic Simulator v1. Download Buried Alive VR.
























Open PDFelement on your computer. Next, click on the "Open File" button in the home window. You can also open files by clicking on "File" then "Open" at the main menu. Select the appropriate PDF file and upload it. The uploaded PDF file will then be displayed in a new window. Move to the top menu and click on the "Edit" button in the top left-hand corner.

Text files. How to download video games. Note Many programs may also be included in a compressed file. Tip If you're having trouble figuring out how to install the drivers you have downloaded, look for a readme file with this information. Tip Once an image is saved, you may open it with an image editor or another program that supports the image's file format. Tip You can also choose to copy the image and then paste it into any document or graphics program.

Tip If the browser is opening the document or the link isn't working, you can also right-click the image and choose Save link as , Save target as , or Save linked content as. Tip If the browser is opening the spreadsheet or the link isn't working, you can also right-click the link and choose Save link as , Save target as , or Save linked content as. Note Many websites that grab information from a database do not save the data as a.

Additional information Where are the files I downloaded using my web browser? How to change your browser download location. Why does my download stop before it is finished? How to clear your downloads folder. How to upload and download a file or folder in Google Drive. How to install software. Computer downloads. See the download definition for further information and related links to this term. Internet help and support.

Use the Internet Explorer to navigate web sites and click on files for downloading. Save currently loaded web page or extract resources images, videos, audios, scripts, stylesheets from it. View and update folder's and file's properties specific to particular file type, for example, you can view and update ID3 tags for audio files. Choose how to download and upload files changing application settings. Monitor the transfer queue. Zip and unzip files and folders supporting password protection.

Send files via e-mail using SMTP server of your choice. Send files via bluetooth to any devices such as Android, iPhone, Windows Phone, etc. Share the files with the integrated light FTP server supporting multi-language names. Protect the data with the login PIN. Version 3. Updated OneDrive functionality in accordance to Microsoft changes. Updated GoogleDrive functionality in accordance to Google changes. Fixed Dropbox authorization issue introduced by Dropbox stopped supporting Edge 18 web browser.

Collectives on Stack Overflow. Learn more. How to download a file and store it in Downloads folder using Flutter Ask Question. Asked 2 years, 2 months ago. Active 1 month ago. Viewed 24k times. Is there an option to do so without using any 3rd-part libraries? Improve this question. Eliya Cohen Eliya Cohen 8, 8 8 gold badges 47 47 silver badges 89 89 bronze badges. Is it fine if using dio?

AmitPrajapati that's fine — Eliya Cohen. Amit the implementation you wrote works, but I was hoping for a shorter implementation.

From this point on, your Web application should be able to successfully connect to your SQL Server database. Wonder where to go next? You can post a comment on this article. I am interested in what you have to say about this article. Feel free to post any comments, remarks or questions you may have about this article.

The Talk Back feature is not meant for technical questions that are not directly related to this article. Also spam and unrealistic job offers will be deleted immediately.

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These are intended to give us a better idea of just how many apps are being downloaded every year, which of these are most popular, and how they are being used. We have collected data and statistics on iOS and Android app downloads. Read on below to find out more. By signing up you agree to our privacy policy. You can opt out anytime. Industry-specific and extensively researched technical data partially from exclusive partnerships.

A paid subscription is required for full access. Additional Information. As a Premium user you get access to the detailed source references and background information about this statistic. As a Premium user you get access to background information and details about the release of this statistic. This feature is limited to our corporate solutions.

Please contact us to get started with full access to dossiers, forecasts, studies and international data. You only have access to basic statistics. This statistic is not included in your account. Skip to main content Try our corporate solution for free!

Single Accounts Corporate Solutions Universities. Obviously, nobody will be able to download your app if this happens. Those categories have more competition. As I just said, the mobile app industry is highly competitive. But how many apps are going to be competing with?

Take a look at the number of apps available on the Apple App Store. The number of available apps is continuing to rise each year. More people have mobile devices than ever before, and app downloads are at an all-time high.

But are app download numbers on the rise because more apps are available? Or are more apps available because so many more apps have been released? I took the time to create a more in-depth analysis of the Google Play Store. We just finished looking at the Apple App Store availability. So I wanted to jump right in and show you the number of apps available for download on the Google Play Store. We actually saw a drop in app availability after mid Although the number of apps have been steadily rising ever since.

The Google Play Store is highly competitive. Based on the data over the past two years, the trend line should continuing rising for the foreseeable future. As we already saw, Google Play Store downloads are still rising, even though the number of apps available for download had dropped a bit during that same period.

The Apple App Store app availability numbers are rising each year, but the download growth rate is a lower percentage compared to the Google Play Store. You can measure the success of an app category based on penetration. According to Statista, these are the app categories with the highest penetration rate among Android users. Some of these categories need to be taken with a grain of salt. For example, look at the top categories on the list. Those apps such as communication apps likely come pre-loaded on all Android devices.

But aside from that, this list is a good indication of what types of apps Android users have downloaded apps like WhatsApp, Snapchat, Netflix, TikTok, Spotify, and Tinder. The average smartphone user spends 3 hours and 10 minutes each day using their device. The average person uses 9 mobile apps per day and 30 apps per month. What does this mean? People are downloading apps and not using them. As you just learned, app usage is not guaranteed after a download.

Some of you might be aware of this if your app has already been brought to market. But how do you know if this is happening to you? Apple and Google have both, for the past three years, added more barriers to entry for developers. They have also purged millions of apps from their respective stores, in an attempt to improve quality across the ecosystem. These account for approximately 75 percent of all app downloads in China.

Apple is able to continue to operate in China with its app store, although the Chinese government regularly sweep the store to remove apps and games. Analyse your app, build better products and user experience. At the back of App Store domination in terms of generating high revenue for the developers with the reason behind why iPhone developers earn more being evident , the number of publishers who have become a part of this app store trend is , While App Store continues to fall behind Play Store when it comes to the mobile app download statistics , within the platform itself, the number of downloads between and has shown a rise of App Store has been witnessing a growing trend in demand for apps to be used through Apple Watches.

This data is a sign of how the users are expanding beyond their smartphones for being active on their favorite apps, along with brands exploring the way for developing and marketing an App Watch app.

Here are the app categories that are topping the App Store in Subscription based apps are finding themselves in the middle of an uprising demand from the millions of app users on the Apple Store.

The trend that was started by Netflix is what has led to a number of other businesses entering into the segment with their subscription based apps. And the demand for these apps is so much so that they are playing a very huge role in the app sales statistics chart of the App Store. Wish to join the growth tangent that the app category is on?

Know how much Netflix like subscription app development would cost. Here are the top apps in the Apple App Store in —. While the Internet is filled with articles on how to increase the star rating of your app, the store has a different story to tell.

Not every app on the store has a rating and yet they are all operating side by side with the apps that have the ratings.
























The guide we offer below will work on both Chrome and Firefox. For the most part the guide should be quite straightforward on other browsers so long as you know how to save images.

The guide above is for when an image defaults to. If you are in the Twitter app, saving an image is much easier. Simply tap on the image itself to bring it into full screen. Next, tap the three dots in the top right corner, and then tap Save. The image will save to a folder on your phone storage called Twitter.

If you right click a video and click save as, it will ask if you want to save the entire webpage instead. Before we begin, please keep in mind that you should be wary of using such services. These websites usually work without any issue. A quick Google search will return a currently available Twitter video downloader. For example, we used DownloadTwittervideo. Once on the website, copy and paste the video link from Twitter. To get the full link, you need to click on the card to bring it into full screen view.

You can then paste that link into the video downloader website, then click download. Once you click the download button, your browser will begin to download a. Follow the steps below to get the video link. You can now search for a Twitter video downloader in Google and paste the link. The video will download to your downloads folder by default. When you see these pictures, you might wonder how to download Twitter pictures. Luckily, this post will show you how to download Twitter pictures in 3 ways.

And if you want to create a picture slideshow, MiniTool MovieMaker should be given priority. In the previous articles, you have already known how to download all photos from Google and how to download Facebook photos.

Twitter is also a popular social networking service and used to share images, videos, and other content. This post will focus on how to download Twitter pictures. Step 5. Click the Save button in the upper-right corner to save the picture to your Android storage.

Step 1. And it also allows you to download Twitter videos.
























No credit card required Get started Get a free consultation. Business Workflow Apps Automate business processes and make your team more efficient. Employee Communication Apps Immediately improve engagement and compliance with capabilities only available in a mobile app.

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Seizure warnings Photosensitive seizure warning. Report this product Report this app to Microsoft Thanks for reporting your concern. Our team will review it and, if necessary, take action.

Sign in to report this app to Microsoft. Report this app to Microsoft. Report this app to Microsoft Potential violation Offensive content Child exploitation Malware or virus Privacy concerns Misleading app Poor performance.

How you found the violation and any other useful info. As long as you are not using your app for commercial reasons, it's all free. MobiRoller is a mobile app making platform that anyone can build a mobile app without coding.

We are a transparent company and product suggestions are highly welcomed since we put user and customer happiness at first place. We would like to help entrepreneurs and freelancers a lot so if you begin your app journey with us, we will move forward fast. Faster development Why spend time and money building applications the traditional way when you can do it easier and faster with us? Offline access Access your app and add data when you're offline. Built-in integrations Zoho Creator is integrated with over 40 other Zoho products, as well as a host of popular third-party applications.

Read more. PWA Native mobile app. Instant media upload Capture images, audio, and video with your device, and upload them for instant access. Gesture control Now, the power is at your finger tip, literally.

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Locale Emulator Yet another system region and language simulator. SourceForge is not affiliated with Locale Emulator. Add a Review. Get project updates , sponsored content from our select partners, and more.

Full Name. Phone Number. Job Title. Company Size Company Size: 1 - 25 26 - 99 - - 1, - 4, 5, - 9, 10, - 19, 20, or More. Get notifications on updates for this project. Get the SourceForge newsletter. JavaScript is required for this form. No, thanks. Summary Files Reviews. Features Provides a simulation function that can make an application recognize your OS Play country-specific games Locale Emulator supports bit executables running on both bit or bit systems System region and language simulation Similar to AppLocale and NTLEA.

Project Samples. Project Activity. Mit einem Experten sprechen. User Reviews Be the first to post a review of Locale Emulator! Report inappropriate content. I have the same question Report abuse. Details required :. Cancel Submit. Nithyananda J. Hi, You can try the following methods. Method 1: You may try to unregister Windows Installer, and then re-register Windows Installer and check if the issue persists. How satisfied are you with this reply? Thanks for your feedback, it helps us improve the site.

There are still links from people who saved and kept the msi file and re-upped it, just search around more thoroughly. A subscription to make the most of your time.
























Wondering what the next steps are? Don't worry. We want the best for our customers, so you have any comments or suggestions regarding this topic, please send us an email to the Cisco Content Team. By the way, once the configurations are complete on the router, you can view your connection on the lower right-hand of your screen. Click the up arrow and hover over the AnyConnect icon to see the details.

In order to utilise the maximum potential of this app, you need some technical knowledge. Moreover, you can expect regular updates to fix errors and bugs. Since Cisco AnyConnect is backed by a solid community , you can even access numerous forums online.

However, the application requires Java Runtime installed on your PC. Considering everything, Cisco AnyConnect is a secure and safe way to surf the internet. It ensures uninterrupted connectivity for your workforce. We don't have any change log information yet for version 4. Sometimes publishers take a little while to make this information available, so please check back in a few days to see if it has been updated. If you have any changelog info you can share with us, we'd love to hear from you!

Head over to our Contact page and let us know. Hotspot Shield is a VPN service, allowing you to surf the internet anonymously. With this program, you can get complete privacy and security over the internet. With more than 2, servers around the. OS does not allow profile name to contain special characters so the name must be edited before saving.

Please utilize the full AnyConnect application from your IT Department if additional features are needed. Stay informed about special deals, the latest products, events, and more from Microsoft Store. Available to United States residents. By clicking sign up, I agree that I would like information, tips, and offers about Microsoft Store and other Microsoft products and services. Privacy Statement. See System Requirements. Description Please direct any questions, feedback or problem reports to ac-mobile-feedback cisco.

Show More. When installer begins installation you will see Click Finish when prompted to complete installation. Connect Launch Cisco AnyConnect. Non-Duo single-factor authentication : vpn. A free Android emulator for Windows. Easy editing of your personal memories. Treesize makes sure that it will not happen to you. Free PvP tactical shooting game.

Gold-standard in cyber security Protect yourself from hacking and data breaches with the best cyber security program available today The Cisco AnyConnect Secure Mobility Client has raised the bar for end users who are looking for a secure network. Connect with Ease AnyConnect 4. Where can you run this program? Our take Cisco AnyConnect Secure Mobility is a great solution for creating a flexible working environment. Should you download it? It is an excellent investment, and definitely worth downloading to your smartphone and PC.

Highs Complete user access Insightful user and endpoint behavior Single agent management Multiple Integrations.
























Skills are increased by the number of times used. For example, use any specifically chosen skill, whether it is necessary or not for that battle, each turn, against weaker enemies- like heal spells, and various elemental and physical attacks- maybe certain buffs and debuffs, if you desire. Keep attacking and healing with your favorite skills whether or not you need that specific attack, or whether or not you need that specific healing ability.

Just do it every turn and every battle, until you increase the strength of the abilities to a comfortable or OP level. Utilize that feature! Going through this entire process will prove to be a useful strategy, and we will be thankful for it, as we get deeper into the game. The early efforts of repeated mundane battles and attacks, will pay off with being able to use OP skills and techniques against otherwise deadly enemies.

In Antiquia Lost, as the party gains Trust through designated events and items, three teammates improve a unique skill that can be used outside the battlefield. One character can pick locks, one can crush rocks, and one can squeeze into small places- like mouse holes. In that case, make note of the location of the lock, rock, or hole, and return to it later to claim the treasure behind it.

On top of that, each char can learn every elemental magic spell. Having five different types of skills which includes Meteorite , and some of the learned skills end up creating two pages, it can make the scrolling to reach the appropriate attack or measure a little cumbersome.

Battles are turn-based. The gameplay is largely linear. That is not so unusual for RPGs. At certain points in the game, other areas to explore become available. There is post-game content to play. The graphics are crystal clear. Artwork is beautiful. The dialogue is redundant or unrealistic, and it is often pointless. This game could probably be played without any dialogue at all. The potential for a great or better written story is most certainly there. There is considerable mystery surrounding the NPC, Alma.

Without Alma and everything that surrounds him, the game would flatline. To look deeper into the storyline, it does appear that Alma is more than one vital organ for the game. Regardless of any less-than-stellar review I write, I enjoyed this game immensely.

Antiquia Lost is reminiscent of old-school bit console games that have been re-mastered. It has a pleasantry about it that makes anything that could be undesirable just fade into the background while you play. User reviews rating score: 3. Battle System:.

Skill System:. Sign In. Home Discussions Workshop Market Broadcasts. Change language. Install Steam. Your Store Your Store. Categories Categories. Special Sections. Player Support. Community Hub. Antiquia Lost. Exe Create Inc. An authentic RPG of a journey with a girl made of slime!

Enjoy fluid 2D turn-based battles! Bine is a young man who lives in a small rural village. One day, he is asked by Lunaria, a girl who lives near the village, to go with her to the royal capital All Reviews:. Popular user-defined tags for this product:. Is this game relevant to you? Sign In or Open in Steam. Languages :. English and 1 more. Share Embed. Add to Cart. View Community Hub. One day, he is asked by Lunaria, a girl who lives near the village, to go with her to the royal capital.

Age rating For ages 7 and up. Category Role playing. This app can Access your Internet connection Access your Internet connection and act as a server. Permissions info. Publisher Info Antiquia Lost support. Report this product Report this game to Microsoft Thanks for reporting your concern. Our team will review it and, if necessary, take action. Sign in to report this game to Microsoft.

Report this game to Microsoft. Report this game to Microsoft Potential violation Offensive content Child exploitation Malware or virus Privacy concerns Misleading app Poor performance.

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The text will fall under the person who sent it and it will have the following:. At this point, I am ready to give up on Samsung. The service location could not resolve the issue and told me that I would have to send the phone into the service center without a temp being provided. Obviously, sending my phone in without a back up is not an option. I have been having this issue for about two months now. It happens when I am on my mobile data only and wifi only.

If anyone has any ideas, I would greatly appreciate it. This is my last ditch effort before I move unhappily away from Samsung and to an iPhone. Go to Solution. Here: How to backup your Android phone. You can go to your carrier and seek assistance. There are also third-party options. You can connect one-on-one with an electronics expert through JustAnswer , an Android Authority partner.

Is your messaging app no working? Try these fixes Staying in touch isn't easy without your messaging app! How To By John Callaham. Outages and reception While very uncommon, there is a chance your carrier network is having an outage. More: Common Android issues and how to fix them Restart the phone This is a very common troubleshooting tip. Check your mobile plan. Also read: The best phone plans for every type of user Clear the cache and data Cache data is good for keeping your device snappy.

How to clear cache and data on Android: Open the Settings app. Go into Apps. Find the Messages app under See all apps. Hit Clear Cache. You can also select Clear storage for a clean start. So, we thought to compile the solution for this issue here and let our readers familiar with the issue. Folks, who are facing this issue can perform the steps stated here to resolve the problem. The whole solution to this problem is to clear the cache.

Let me make you familiar with the word Cache. When you are using any website or any app, the applications start storing some files for future references. It includes the password, cookies, URL, and some other information also.

The data is saved in the cache of the app. Before you begin to fix your device stuck in download mode, make sure that all your phone data is backed up to prevent data loss. Android Data Extraction software comes in handy when you need to back up your data, just by following the simple steps outlined above. And whether you choose to use the first method where no firmware is used or the second which entails installation of firmware software, you are assured of success in the end.

In addition, in case any queries arise feel free to contact us. In Repair Android. Android Stuck in Download Mode [Fixed]. Download Win Download Mac Follow the following steps and you are on a clear path to recover data on your Samsung device: Step 1: Download and install Android Data Extraction on your computer then click on recover.

Download Win Download Mac How to Exit Samsung Download Mode Now that all the data is stored in a safe place, you should start the process of exiting the Samsung download mode and ensure that your device runs as intended.

Just wait for about 1 minute and it will to recovery mode. Conclusion Before you begin to fix your device stuck in download mode, make sure that all your phone data is backed up to prevent data loss.
























Sign up or log in Sign up using Google. Sign up using Facebook. Sign up using Email and Password. Post as a guest Name. Email Required, but never shown. The Overflow Blog. Podcast what if you could invest in your favorite developer? Who owns this outage? Building intelligent escalation chains for modern SRE. Featured on Meta. Now live: A fully responsive profile. Reducing the weight of our footer. Linked 0. Related Run apps on the emulator. Run apps on a hardware device. Configure your build.

Optimize your build speed. Debug your app. Test your app. Profile your app. Android Studio profilers. Profile CPU activity. Benchmark your app. Measure performance. Publish your app. Command line tools. Android Developers. To add support for Android App Links: Create intent filters in your manifest. App navigation. Navigation component. App links. Dependency injection. Core topics. App compatibility. Interact with other apps. Package visibility. Intents and intent filters.

User interface. Add motion to your layout with MotionLayout. MotionLayout XML reference. Improving layout performance. Custom view components. Look and feel. Splash screens. Add the app bar. Control the system UI visibility. Supporting swipe-to-refresh. Pop-up messages overview. Adding search functionality. Creating backward-compatible UIs. Home channels for mobile apps.

App widgets. Media app architecture. Building an audio app. Building a video app. The Google Assistant. Routing between devices. Background tasks. Manage device awake state. Save to shared storage. Save data in a local database.

Sharing simple data. Sharing files. Sharing files with NFC. Printing files. Content providers. Autofill framework. Contacts provider. Data backup. Remember and authenticate users. User location. Using touch gestures. Handling keyboard input. Supporting game controllers. Input method editors. Performing network operations. Transmit network data using Volley. Perform network operations using Cronet. Transferring data without draining the battery. Reduce network battery drain.

Transfer data using Sync Adapters. Bluetooth Low Energy. Wi-Fi infrastructure. Discover and connect. Runtime API reference. Web-based content. Android App Bundles. Google Play. Play Asset Delivery. Play Feature Delivery. In-app reviews. In-app updates.
























Common Emergency Drugs in Casualty Wards. Anemia: The Clinical Approach you never knew. You can download or read online the Robbins Basic Pathology 9th Edition book by links given below. You can mail us if you need latest editions of the book such as 10th, 11th or 12th edition of Robbins Basic Pathology. If the links are not working, do let us know using the comments section, we will readily update it. If you are unable to locate the links, please refresh the page.

If you need other books, do check out our Downloads Section. Please note these are external links and we do not host any downloads on our website. If you are the owner of the content or have disputes regarding the terms, please read our complete Disclaimer page or leave us a message via our Contact Us page. Any violation or infringement will be immediately removed upon confirmation. Please try to get a link of latest edition of it!

Plea send me an e-copy of the latest edition 10th of Robins Pathology on my e-mail …. You may send an email to arshadullahbangash gmail. Comments I want step up to medicine 5th edition PDF. Your email address will not be published. Scoliosis is an abnormal lateral curvature of the spine, accompanied by rotation of the vertebrae. Spondylolisthesis: The lumbosacral angle is created between the long axes of the lumbar vertebrae and the sacrum. It is primarily because of the anterior thickness of the L5 body.

As the line of body weight passes anterior to the SI joints, anterior displacement of L5 over S1 may occur spondylolisthesis , applying pressure to the spinal nerves of the cauda equina. They drain into the valveless vertebral venous plexus. The anesthetic solution spreads superiorly to act on spinal nerves S2-Co.

The height to which the anesthetic ascends is affected by the amount of solution injected and the position of the patient. Spinal block: Introduction of an anesthetic directly into the CSF in the subarachnoid space utilizing a lumbar puncture see above. Subsequent leakage of CSF may cause a headache in some individuals. Radiation to back of the thigh and into the leg sciatica or focal neurology suggests radiculopathy. Back strain: Stretching and microscopic tearing of muscle fibres or ligaments, often because of a sport-related injury.

The muscles subsequently go into spasm as a protective response causing pain and interfering with function. This is a common cause of low back pain. Frequently caused by impacts from the rear in motor vehicle accidents. May cause herniation of the IV disc and subsequent radiculopathy. The thoracic cage protects the contents of the thorax, whereas the muscles assist in breathing. It is important to identify and count ribs as they form key landmarks to the positions of the internal organs.

Midaxillary lines are perpendicular lines through the apex of the axilla on both sides Cephalic vein can be seen in some subjects lying in the deltopectoral groove between the deltoid and pectoralis major muscles. This is called a median sternotomy. The middle ribs are most commonly fractured, and multiple rib fractures can manifest as a "flail chest," where the injured region of the chest wall moves paradoxically, that is, in on inspiration and out on expiration.

The glands are rudimentary in males and immature females. Size and shape of the adult female breast varies; the size is determined by the amount of fat surrounding the glandular tissue.

The base of the breast is fairly consistent extending from the lateral border of the sternum to the midaxillary line and from the 2nd to the 6th ribs. The majority of the breast overlies the deep pectoral fascia of the pectoralis major muscle, with the remainder overlying the fascia of the serratus anterior. The breast is separated from the pectoralis major muscle by the retromammary space, a potential space filled with loose connective tissue.

The breast is firmly attached to the overlying skin by condensation of connective tissue called the suspensory ligaments of Cooper , which help to support the lobules of the breast. Asmall part of the mammary gland may extend toward the axilla, called the axillary tail of Spence. Structure of the Breast For descriptive purposes, the breast is divided into four quadrants: upper and lower lateral, and upper and lower medial.

The most prominent feature of the breast is the nipple. The nipple is surrounded by the areola, a circular pigmented area of skin. The areola is pink in Caucasians and brown in African and Asian people. The pigmentation of the areola increases during pregnancy. The areola contains sebaceous glands, following a pregnancy these secrete an oily substance to protect the mother's nipple from irritation during nursing.

The breast is composed of 15 to 20 lobules of glandular tissue, formed by the septa of the suspensory ligaments. The mammary glands are modified sweat glands that are formed from the development of milk-secreting alveoli, arranged in clusters. Each lobule is drained by a lactiferous duct Each lactiferous duct opens on the nipple.

The breast is also supplied by the branches of the thoracoacromial and lateral thoracic arteries from the axillary artery. Venous drainage parallels the arterial supply and is mainly to the axillary artery and internal thoracic vein. Lymphatic Drainage of the Breast [Plate , Lymph Vessels and Nodes of Mammary Gland] Lymph from the nipple, areola, and lobules of the mammary glands drains to a subareolar lymphatic plexus.

From there, a system of interconnecting lymphatic channels drains lymph to various lymph nodes. The majority of the lymph, especially from the lateral quadrants of the breast, drains to the pectoral nodes, and from there to the axillary nodes. The remaining amount of lymph, especially from the medial quadrants of the breast, drains into the parasternal lymph nodes along the internal thoracic vessels. Some lymph from the lower quadrants of the breast passes to the inferior phrenic nodes.

It is important to note that lymph from the medial quadrants can cross to the opposite breast. Thus secondary metastases of breast carcinoma can spread to the opposite breast in this way.

The palpation should extend into the axilla to palpate the axillary tails. After palpation of one breast, the other should be palpated in the same way. Examine the skin of the breast for a change in texture or dimpling peau d'orange sign and the nipple for retraction, since these signs may indicate an underlying pathology.

Pathology of the Breast Fibroadenoma: benign tumor, usually a solid and solitary mass that moves easily under the skin. Often painless although sometimes tender on palpation. More common in young women but can occur at any age.

Intraductal carcinoma or breast cancer: the commonest type of malignancy in women but can also occur in men. This malignancy presents as a palpable mass that is hard, immobile and sometimes painful. Additional signs can include bloody or watery nipple discharge if the larger ducts are involved. Gynecomastia: enlargement of the breasts in males because of aging, drug treatment, and changes in the metabolism of sex hormones by the liver.

External intercostal muscles: Have fibers that slope down and medially. Extend from the posterior tubercle of the rib to the junction of the rib and its costal cartilage anteriorly. Anteriorly, are replaced by external intercostal membranes that extend from the costochondral junctions to the sternum. Internal intercostal muscles: Lie internal to the external intercostal muscles Their fibers lie at right angles to those of the external intercostal muscles and run inferiorly and laterally.

Anteriorly extend to the lateral border of the sternum. Posteriorly extend only to the angles of the ribs; medial to the angles, are replaced by the internal intercostal membranes. Innermost intercostal muscles Lie deep to the internal intercostal muscles Are separated from the internal intercostals by the intercostal vessels and nerves Occupy the middle parts of the intercostal spaces Connect inner surfaces of adjacent ribs All intercostal muscles are supplied by intercostal nerves corresponding in number to their intercostal space.

Main action of the intercostals is to maintain the space between the ribs during inspiration and expiration. Other muscles of the rib cage Subcostal muscles-internal to the internal intercostals, cross from the angle of one rib to internal surface of the rib 1 to 2 spaces below.

Transversus thoracis-4 to 5 slips of muscle that attach to the xiphoid process and inferior sternum and pass superiorly and laterally to attach to the 2nd through 6th costal cartilages. Muscular branches supply the intercostal, levatores costarum, transversus thoracis, and serratus posterior muscles. The lower five intercostal nerves supply the skin and muscles of the abdominal wall Contain general somatic afferent and efferent fibers, as well as general visceral efferent fibers from the sympathetic trunk via white and grey rami communicantes and general visceral afferent fibers.

Ribs 1 through 7 are vertebrocostal because they attach to the sternum via a costal cartilage. Ribs 8 through 10 are vertebrochondral because their cartilages are joined to the cartilage of the rib above and via that connection to the sternum.

Ribs 11 and 12 are free or floating ribs, which do not connect even indirectly with the sternum but which have a costal cartilage on their tips. First rib is broad and sharply curved and has a tubercle of the attachment of scalene muscles. To avoid damage to the intercostal vein, artery, and nerve that run in the costal groove on the inferior surface of each rib, the needle is inserted well below the rib. The needle also must be placed sufficiently above the rib below to avoid the collateral branches of intercostal nerve and vessels that run along the superior surface of each rib.

They articulate with the C7 vertebra, but do not attach to the sternum. They may fuse with the first rib. If a cervical rib is present, however, it may compress the subclavian artery or inferior trunk of the brachial plexus and cause ischemic pain and numbness in the shoulder and upper limb.

This condition is called thoracic outlet syndrome. Bone Marrow Biopsy and Aspiration. Bone marrow aspiration and biopsy help diagnose many blood disorders and can be used to detect if cancer has spread to the bone marrow. Bone marrow biopsy: The removal of bone and marrow for examination under the microscope. The sternum is a site of red marrow, even in adulthood, and is a good site for a bone marrow biopsy. Another common site is the posterior iliac crest.

Abiopsy is usually conducted before performing a bone marrow aspiration. Bone marrow aspiration: The removal of a small amount of bone marrow fluid through a needle inserted into the bone. Fluid is examined to determine if there are any problems with the blood cells made in the bone marrow Mnemonics Memory Aids Vertical order of the contents of the neurovascular bundle in the costal groove on the lower border of each rib: VAN Vein, Artery, Nerve.

The pleural cavity contains a thin layer of serous pleural fluid, which lubricates and allows the pleurae to move smoothly over each other during respiration. Surface tension keeps the lung surface in contact with the thoracic wall. The lung expands and fills with air when the thoracic cavity expands. The sternal line of pleural reflection is the sharp line along which the costal pleura becomes the mediastinal pleura The costal line of pleural reflection is the sharp line along which the costal pleura becomes the diaphragmatic pleura The vertebral line of pleural reflection is a smooth reflection of the costal pleura onto the vertebrae posteriorly.

The lines of pleural reflection on the left side can be remembered as The line of pleural reflection on the left descends in the midline of the sternum to the 4th costal cartilage, where it deviates to the left margin of the sternum at the 6th costal cartilage to accommodate the pericardium and the heart cardiac notch.

This line then deviates to cross the 8th rib at the midclavicular line. It crosses the 10th rib at the midaxillary line It then crosses the 12th rib at approximately the neck. On the right side, the line of pleural reflection descends at the midline of the sternum to the xiphoid process, and then deviates The lungs do not fully occupy the pleural cavities during expiration There are peripheral areas where the diaphragmatic and costal pleura come in contact and these are called the costodiaphragmatic recesses.

There are areas posterior to the sternum where the costal and mediastinal pleura come in contact with each other, and these are called costomediastinal recesses. The costomediastinal recess is larger on the left, because of the cardiac notch. During expiration, the lower limit of the lungs is two costal spaces above the line of pleural reflection: the sixth rib at the midclavicular line, the 8th rib at the midaxillary line, and the 10th rib at the neck.

Thus the costodiaphragmatic recess is approximately two costal spaces deep. The horizontal fissure runs from the oblique fissure at the midaxillary line along the 4th rib to its costal cartilage anteriorly. The anterior margin of the left lung has an indentation-the cardiac notch, which often creates a thin process in the upper lobe called the lingula. Each lung has three surfaces: Costal Mediastinal Diaphragmatic Each lung is connected to the mediastinum by the root of the lung.

Lung root contains: Main stem or lobar bronchi Pulmonary vessels and bronchi. Bronchial vessels, lymphatics, and autonomic nerves. The lung root is surrounded by a pleural sleeve, from which extends the pulmonary ligament inferiorly. The carina is the keel-like ridge between the two openings of the main stem bronchi. The right main stem bronchus divides into upper and lower lobar bronchi before reaching the substance of the right lung.

The main bronchi branch to form the bronchial tree. There are three lobar bronchi on the right: upper, middle, and lower There are two lobar bronchi on the left: upper and lower Each lobar bronchus branches into segmental bronchi that supply a bronchopulmonary segment. Each pulmonary artery gives rise to lobar and segmental arteries.

Intrasegmental veins drain to intersegmental veins in the pulmonary septa, which run a separate course from the pulmonary and segmental arteries and which drain to two pulmonary veins for each lung. Pulmonary veins carry oxygenated blood to the left atrium of the heart. Bronchial arteries from the thoracic aorta carry oxygenated blood to the tissue of the lungs, traveling along the posterior surface of the bronchi. The left bronchial arteries come from the thoracic aorta; the single right bronchial artery may also arise from the superior posterior intercostal or a left superior bronchial artery.

The bronchial arteries anastomose with branches of the pulmonary arteries. Pulmonary veins drain the blood to the lungs supplied by the bronchial veins and empty into the azygos and accessory hemiazygos veins. The lungs have a rich, freely connecting network of lymphatic vessels.

Lymph from the lungs drains to Pulmonary lymph nodes along the lobar bronchi Bronchopulmonary lymph nodes along the main stem bronchi Superior and inferior tracheobronchial lymph nodes superior and inferior to the bifurcation of the trachea Innervation of the lungs Innervation is via the pulmonary plexuses located anterior and posterior to the lung roots. The plexuses contain postganglionic sympathetic fibers from the sympathetic trunks that innervate the smooth muscle of the bronchial tree, pulmonary vessels, and glands of the bronchial tree.

Sympathetic fibers are bronchodilators, vasoconstrictors, and inhibit glandular secretion. The plexuses contain preganglionic parasympathetic fibers from the vagus nerve CN X , small parasympathetic ganglia, and postganglionic parasympathetic nerves that innervate the smooth muscle of the bronchial tree, pulmonary vessels, and glands of the bronchial tree.

Parasympathetic fibers are bronchoconstrictors, vasodilators, and secretomotor to the glands. Pneumonia: a bacterial or viral infection of the lung that can lead to widespread systemic infection and lung collapse. Pneumonia is frequently confined to a single lobe of one lung and is called lobar pneumonia.

It can be clearly seen circumscribed to one lobe in a chest radiograph. The entry of air into a pleural cavity because of a penetrating wound or a fractured rib is called a pneumothorax and results in partial or total collapse of the lung. The escape of fluid into the pleural cavity pleural effusion is called hydrothorax; if the fluid is blood, the condition is known as a hemothorax, and if it is chyle from the thoracic duct, it is called a chylothorax.

Inflammation of the pleurae is called pleuritis or pleurisy; resulting friction between the two pleurae pleural rub is very painful and can be heard with a stethoscope.

The inflamed pleurae may adhere to each other pleural adhesion Squamous cell or oat cell carcinoma is a common cancer of the lung, usually caused by smoking, that may be indicated by a persistent cough or spitting of blood hemoptysis.

The fibrous outer layer of the pericardium the fibrous pericardium consists of dense connective tissue. The fibrous pericardium is attached to the central tendon of the diaphragm by the pericardiacophrenic ligament.

It blends with the tunica adventitia of the vessels entering and leaving the heart. It has ligamentous attachments to the sternum It is thus affected by movements of the heart, the great vessels, the sternum, and the diaphragm. Skin Lesions Melanoma Surgical Intensive Care Pediatric Surgery Plastic Surgery Hand Surgery Otolaryngology: Head and Neck Surgery Thoracic Surgery Cardiovascular Surgery Transplant Surgery Orthopaedic Surgery Neurosurgery Urology Ophthalmology Figure Credits Index Click it to start your free download now.

Tuesday, November 23, All Things Medicine. The study of neuroanatomy is described best by this snell book and its 8th edition proves the amount of importance it has for students. Download it now along with the gross anatomy snell. Other family members and associates include Paul Splittgerber and Kelly Splittgerber. Splittgerber is an amazing anatomist. A great resource for learning anatomy!